3K9N
Allosteric modulation of H-Ras GTPase
Summary for 3K9N
| Entry DOI | 10.2210/pdb3k9n/pdb |
| Related | 2RGE 3K8Y 3K9L |
| Descriptor | GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | protein-nucleotide complex, acetylation, cell membrane, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, s-nitrosylation, oncoprotein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 |
| Total number of polymer chains | 1 |
| Total formula weight | 19445.77 |
| Authors | Fetics, S.,Young, M.,Buhrman, G.,Mattos, C. (deposition date: 2009-10-16, release date: 2010-03-02, Last modification date: 2023-09-06) |
| Primary citation | Buhrman, G.,Holzapfel, G.,Fetics, S.,Mattos, C. Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc.Natl.Acad.Sci.USA, 107:4931-4936, 2010 Cited by PubMed: 20194776DOI: 10.1073/pnas.0912226107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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