3ISS

Crystal structure of enolpyruvyl-UDP-GlcNAc synthase (MurA):UDP-N-acetylmuramic acid:phosphite from Escherichia coli

3ISS の概要

• エントリーDOI: 10.2210/pdb3iss/pdb
• 関連するPDBエントリー: 1A2N 1DLG 1EYN 1Q3G 1UAE 2Z2C
• 分子名称: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, PHOSPHITE ION, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID, ... (4 entities in total)
• 機能のキーワード: protein-ligand, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, peptidoglycan synthesis, transferase
• 由来する生物種: Escherichia coli K-12
• 細胞内の位置: Cytoplasm (Probable): P0A749
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 545997.34

構造登録者

Jackson, S.G.,Zhang, F.,Chindemi, P.,Junop, M.S.,Berti, P.J. (登録日: 2009-08-27, 公開日: 2009-11-24, 最終更新日: 2023-09-06)

• 主引用文献: Jackson, S.G.,Zhang, F.,Chindemi, P.,Junop, M.S.,Berti, P.J.; Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions .; Biochemistry, 48:11715-11723, 2009; PubMed: 19899805; DOI: 10.1021/bi901524q

実験手法

X-RAY DIFFRACTION (2.5 Å)