Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3HV7

Human p38 MAP Kinase in Complex with RL38

Summary for 3HV7
Entry DOI10.2210/pdb3hv7/pdb
Related3GCP 3GCQ 3GCS 3GCU 3GCV 3HV3 3HV4 3HV5 3HV6
DescriptorMitogen-activated protein kinase 14, 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea, octyl beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywordsdfg-out, type iii, rl38, alternative splicing, atp-binding, cytoplasm, kinase, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight41960.91
Authors
Gruetter, C.,Simard, J.R.,Getlik, M.,Rauh, D. (deposition date: 2009-06-15, release date: 2009-11-17, Last modification date: 2023-09-06)
Primary citationKluter, S.,Grutter, C.,Naqvi, T.,Rabiller, M.,Simard, J.R.,Pawar, V.,Getlik, M.,Rauh, D.
Displacement assay for the detection of stabilizers of inactive kinase conformations.
J.Med.Chem., 53:357-367, 2010
Cited by
PubMed: 19928858
DOI: 10.1021/jm901297e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon