3EQL
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
Summary for 3EQL
Entry DOI | 10.2210/pdb3eql/pdb |
Related | 1IW7 1SMY 2A68 2A69 2A6E 2A6H 2BE5 |
Descriptor | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total) |
Functional Keywords | rna polymerase holoenzyme, myxopyronin, antibiotic, transcription regulation, dna-directed rna polymerase, nucleotidyltransferase, transcription, transferase, dna-binding, sigma factor |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 12 |
Total formula weight | 854440.40 |
Authors | Vassylyev, D.G.,Vassylyeva, M.N.,Artsimovitch, I. (deposition date: 2008-09-30, release date: 2008-10-28, Last modification date: 2023-09-06) |
Primary citation | Belogurov, G.A.,Vassylyeva, M.N.,Sevostyanova, A.,Appleman, J.R.,Xiang, A.X.,Lira, R.,Webber, S.E.,Klyuyev, S.,Nudler, E.,Artsimovitch, I.,Vassylyev, D.G. Transcription inactivation through local refolding of the RNA polymerase structure. Nature, 457:332-335, 2009 Cited by PubMed: 18946472DOI: 10.1038/nature07510 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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