2BE5
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin
Summary for 2BE5
Entry DOI | 10.2210/pdb2be5/pdb |
Related | 1IW7 1SMY 2A68 2A69 2A6E 2A6H |
Descriptor | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... (9 entities in total) |
Functional Keywords | rna polymerase holoenzyme, tagetitoxin, antibiotic, transcription regulation, riken structural genomics/proteomics initiative, rsgi, structural genomics, transferase |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 12 |
Total formula weight | 854462.43 |
Authors | Vassylyev, D.G.,Svetlov, V.,Vassylyeva, M.N.,Perederina, A.,Igarashi, N.,Matsugaki, N.,Wakatsuki, S.,Artsimovitch, I.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-10-22, release date: 2005-11-08, Last modification date: 2023-08-23) |
Primary citation | Vassylyev, D.G.,Svetlov, V.,Vassylyeva, M.N.,Perederina, A.,Igarashi, N.,Matsugaki, N.,Wakatsuki, S.,Artsimovitch, I. Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12:1086-1093, 2005 Cited by PubMed: 16273103DOI: 10.1038/nsmb1015 PDB entries with the same primary citation |
Experimental method |
Structure validation
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