3EGI
Methyltransferase domain of human trimethylguanosine synthase TGS1 bound to m7GpppA (inactive form)
Summary for 3EGI
Entry DOI | 10.2210/pdb3egi/pdb |
Descriptor | Trimethylguanosine synthase homolog, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | methyltransferase-domain, alpha-beta-alpha sandwich, methyltransferase, nucleus, transcription, transcription regulation, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q96RS0 |
Total number of polymer chains | 4 |
Total formula weight | 92891.01 |
Authors | Monecke, T.,Dickmanns, A.,Ficner, R. (deposition date: 2008-09-10, release date: 2009-03-31, Last modification date: 2012-04-18) |
Primary citation | Monecke, T.,Dickmanns, A.,Strasser, A.,Ficner, R. Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1. Acta Crystallogr.,Sect.D, 65:332-338, 2009 Cited by PubMed: 19307714DOI: 10.1107/S0907444909003102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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