3DX3
Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol
Summary for 3DX3
| Entry DOI | 10.2210/pdb3dx3/pdb |
| Related | 1HTY 1HWW 1HXK 1PS2 1QWN 1R33 1R34 1TQV 2ALW 2F7O 2F7P 2F7Q 2F7R 2FYV 3BUB 3BUP 3CZN 3DX0 3DX1 3DX2 3DX4 |
| Descriptor | Alpha-mannosidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total) |
| Functional Keywords | gh38 glycosidase, glycosidase, golgi apparatus, hydrolase, membrane, metal-binding, signal-anchor, transmembrane |
| Biological source | Drosophila melanogaster (Fruit fly) |
| Total number of polymer chains | 1 |
| Total formula weight | 120350.52 |
| Authors | Kuntz, D.A.,Rose, D.R. (deposition date: 2008-07-23, release date: 2009-07-07, Last modification date: 2023-08-30) |
| Primary citation | Kuntz, D.A.,Zhong, W.,Guo, J.,Rose, D.R.,Boons, G.J. The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A. Chembiochem, 10:268-277, 2009 Cited by PubMed: 19101978DOI: 10.1002/cbic.200800538 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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