3BR1

Crystal Structure of the Complex of Dequalinium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor

Summary for 3BR1

• Entry DOI: 10.2210/pdb3br1/pdb
• Related: 1JT6 1JTY 1JUP 1JUS 3BQZ 3BR0 3BR2 3BR3 3BR4 3BR5 3BR6
• Descriptor: HTH-type transcriptional regulator qacR, SULFATE ION, DEQUALINIUM, ... (4 entities in total)
• Functional Keywords: qacr, multidrug resistance, tetr, dequalinium, dna-binding, plasmid, repressor, transcription, transcription regulation
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 4
• Total formula weight: 94498.20

Authors

Brooks, B.E. (deposition date: 2007-12-20, release date: 2008-12-23, Last modification date: 2023-08-30)

• Primary citation: Brooks, B.E.,Hardie, K.M.,Brown, M.H.,Skurray, R.A.,Brennan, R.G.; Formal electrostatic interactions do not govern QacR-cation affinity; To be Published,

Experimental method

X-RAY DIFFRACTION (3.31 Å)