3BR1
Crystal Structure of the Complex of Dequalinium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, D, A, E | HTH-type transcriptional regulator qacR | polymer | 194 | 22982.0 | 4 | UniProt (P0A0N3) Pfam (PF00440) Pfam (PF08360) In PDB | Staphylococcus aureus | |
2 | E, B, D, A | SULFATE ION | non-polymer | 96.1 | 22 | Chemie (SO4) | |||
3 | A | DEQUALINIUM | non-polymer | 456.7 | 1 | Chemie (DEQ) | |||
4 | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
B, D, A, E: 1 - 188 (UniProt: P0A0N3)
PDB | External Database | Details |
---|---|---|
Ala 72 | Cys 72 | engineered mutation |
Gln 90 | Glu 90 | engineered mutation |
Ser 141 | Cys 141 | engineered mutation |
His 189 | - | expression tag |
His 190 | - | expression tag |
His 191 | - | expression tag |
His 192 | - | expression tag |
His 193 | - | expression tag |
His 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 91928.1 | |
Non-Polymers* | Number of molecules | 23 |
Total formula weight | 2570.1 | |
All* | Total formula weight | 94498.2 |