3AM7

Crystal structure of the ternary complex of eIF4E-M7GTP-4EBP2 peptide

Summary for 3AM7

• Entry DOI: 10.2210/pdb3am7/pdb
• Related: 1WKW
• Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 2, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: cap, translation, protein-protein complex, translation-protein binding complex, translation/protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 25109.09

Authors

Tomoo, K.,Fukuyo, A.,In, Y.,Ishida, T. (deposition date: 2010-08-17, release date: 2011-08-17, Last modification date: 2024-05-29)

• Primary citation: Fukuyo, A.,In, Y.,Ishida, T.,Tomoo, K.; Structural scaffold for eIF4E binding selectivity of 4E-BP isoforms: crystal structure of eIF4E binding region of 4E-BP2 and its comparison with that of 4E-BP1.; J.Pept.Sci., 17:650-657, 2011; PubMed: 21661078; DOI: 10.1002/psc.1384

Experimental method

X-RAY DIFFRACTION (2.2 Å)