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3AM7

Crystal structure of the ternary complex of eIF4E-M7GTP-4EBP2 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Eukaryotic translation initiation factor 4Epolymer19122288.31UniProt (P06730)
Pfam (PF01652)
Homo sapiens (human)eIF-4E, eIF4E, mRNA cap-binding protein, eIF-4F 25 kDa subunit
2B
(B)
Eukaryotic translation initiation factor 4E-binding protein 2polymer192282.61UniProt (Q13542)Homo sapiens (human)eIF4E-binding protein 2, 4E-BP2
3C
(A)
7-METHYL-GUANOSINE-5'-TRIPHOSPHATEnon-polymer538.21Chemie (MGP)
4D, E
(A, B)
waterwater18.093Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24570.9
Non-Polymers*Number of molecules1
Total formula weight538.2
All*Total formula weight25109.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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