3ZTD
pVHL54-213-EloB-EloC complex _ methyl 4-(((2S,4R)-4-hydroxy-1-(2-(3- methylisoxazol-5-yl)acetyl)pyrrolidine-2-carboxamido)methyl)benzoate
Summary for 3ZTD
Entry DOI | 10.2210/pdb3ztd/pdb |
Related | 1LM8 1LQB 1VCB 2C9W 2IZV 2XAI 3ZRC 3ZRF 3ZTC |
Descriptor | TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR, ... (5 entities in total) |
Functional Keywords | transcription, tumour supressor protein, pvhl e3 ubiquitin ligase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus (Probable): Q15370 Q15369 Isoform 1: Cytoplasm. Isoform 3: Cytoplasm: P40337 |
Total number of polymer chains | 12 |
Total formula weight | 172904.40 |
Authors | VanMolle, I.,Buckley, D.L.,Crews, C.M.,Ciulli, A. (deposition date: 2011-07-07, release date: 2012-07-25, Last modification date: 2023-12-20) |
Primary citation | Van Molle, I.,Thomann, A.,Buckley, D.L.,So, E.C.,Lang, S.,Crews, C.M.,Ciulli, A. Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. Chem.Biol., 19:1300-, 2012 Cited by PubMed: 23102223DOI: 10.1016/J.CHEMBIOL.2012.08.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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