3PSE
Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15)
Summary for 3PSE
Entry DOI | 10.2210/pdb3pse/pdb |
Related | 3PT2 |
Descriptor | RNA polymerase, Ubiquitin-like protein ISG15, 1.7.6 3-bromanylpropan-1-amine, ... (5 entities in total) |
Functional Keywords | viral deubiquitinase, 3-aminopropane, intein-mediated ligation, crimean-congo hemorrhagic fever virus, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Crimean-Congo hemorrhagic fever virus More |
Cellular location | Cytoplasm: P05161 |
Total number of polymer chains | 2 |
Total formula weight | 36828.52 |
Authors | Bacik, J.P.,James, T.W.,Frias-Staheli, N.,Garcia-Sastre, A.,Mark, B.L. (deposition date: 2010-12-01, release date: 2011-01-19, Last modification date: 2023-09-20) |
Primary citation | James, T.W.,Frias-Staheli, N.,Bacik, J.P.,Levingston Macleod, J.M.,Khajehpour, M.,Garcia-Sastre, A.,Mark, B.L. Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease. Proc.Natl.Acad.Sci.USA, 108:2222-2227, 2011 Cited by PubMed: 21245344DOI: 10.1073/pnas.1013388108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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