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3PD8

X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution

Summary for 3PD8
Entry DOI10.2210/pdb3pd8/pdb
Related1M5E 3PD9
DescriptorGlutamate receptor 2, ZINC ION, (7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-7-carboxylic acid, ... (7 entities in total)
Functional Keywordsionotropic glutamate receptor glua2, ligand-binding core, agonist complex, membrane protein
Biological sourceRattus norvegicus (brown rat,rat,rats)
More
Total number of polymer chains3
Total formula weight88401.29
Authors
Frydenvang, K.,Kastrup, J.S. (deposition date: 2010-10-22, release date: 2010-12-29, Last modification date: 2023-09-06)
Primary citationFrydenvang, K.,Pickering, D.S.,Greenwood, J.R.,Krogsgaard-Larsen, N.,Brehm, L.,Nielsen, B.,Vogensen, S.B.,Hald, H.,Kastrup, J.S.,Krogsgaard-Larsen, P.,Clausen, R.P.
Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid.
J. Med. Chem., 53:8354-8361, 2010
Cited by
PubMed: 21067182
DOI: 10.1021/jm101218a
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.476 Å)
Structure validation

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