3LO5

Crystal Structure of the dominant negative S17N mutant of Ras

Summary for 3LO5

• Entry DOI: 10.2210/pdb3lo5/pdb
• Related: 4Q21
• Descriptor: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: ras, nucleotide exchange, dominant negative, mg2+, acetylation, cell membrane, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, s-nitrosylation, oncoprotein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side: P01112
• Total number of polymer chains: 3
• Total formula weight: 58292.63

Authors

Nassar, N.,Singh, K.,Garcia-Diaz, M. (deposition date: 2010-02-03, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Nassar, N.,Singh, K.,Garcia-Diaz, M.; Structure of the Dominant Negative S17N Mutant of Ras; Biochemistry, 49:1970-1974, 2010; PubMed: 20131908; DOI: 10.1021/bi9020742

Experimental method

X-RAY DIFFRACTION (2.568 Å)