3IR0

Crystal Structure of Human Insulin complexed with Cu+2 metal ion

Summary for 3IR0
Related1MSO 1TRZ 2QIU 2R34 2R35 2R36
DescriptorInsulin A chain, Insulin B chain, COPPER (II) ION, ... (4 entities in total)
Functional Keywordsinsulin, metal binding, coordination, confromation, bilogical role, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains24
Total formula weight70574.36
Authors
Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-21, release date: 2010-09-01, Last modification date: 2011-07-13)
Primary citationPattabhi, V.,Raghavendra, N.,Rajan, S.S.
Metal induced structural changes observed in Human insulin
To be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
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PDB entries from 2021-06-16