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2ZEV

S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium, IPP and BPH-715

Summary for 2ZEV
Entry DOI10.2210/pdb2zev/pdb
Related2DH4 2E8T 2E8U 2E8V 2E8W 2E8X 2E90 2E91 2E92 2E93 2E94 2E95 2ZEU
DescriptorGeranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, ... (5 entities in total)
Functional Keywordsprenyltransferase, farnesyl pyrophosphate, bisphosphonate, carotenoid biosynthesis, isoprene biosynthesis, multifunctional enzyme, protein transport, transport, transferase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Cellular locationCytoplasm (By similarity): Q12051
Total number of polymer chains2
Total formula weight79790.20
Authors
Guo, R.T.,Chen, C.K.-M.,Cao, R.,Oldfield, E.,Wang, A.H.-J. (deposition date: 2007-12-17, release date: 2008-12-23, Last modification date: 2023-11-01)
Primary citationZhang, Y.,Cao, R.,Yin, F.,Hudock, M.P.,Guo, R.T.,Krysiak, K.,Mukherjee, S.,Gao, Y.-G.,Robinson, H.,Song, Y.,No, J.H.,Bergan, K.,Leon, A.,Cass, L.,Goddard, A.,Chang, T.-K.,Lin, F.-Y.,Van Beek, E.,Papapoulos, S.,Wang, A.H.-J.,Kubo, T.,Ochi, M.,Mukkamala, D.,Oldfield, E.
Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation
J.Am.Chem.Soc., 131:5153-5162, 2009
Cited by
PubMed: 19309137
DOI: 10.1021/ja808285e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.23 Å)
Structure validation

217705

数据于2024-03-27公开中

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