Prolyl tripeptidyl aminopeptidase mutant E636A complexd with an inhibitor

Summary for 2Z3Z

Related2D5L 2DCM 2EEP 2Z3W
DescriptorDipeptidyl aminopeptidase IV, SULFATE ION, [(2R)-1-(L-ALANYL-L-ISOLEUCYL)PYRROLIDIN-2-YL]BORONIC ACID, ... (4 entities in total)
Functional Keywordspeptidase family s9, prolyl oligopeptidase family, serine protease, proline-specific peptidase, hydrolase
Biological sourcePorphyromonas gingivalis
Total number of polymer chains1
Total molecular weight79941.98
Xu, Y.,Nakajima, Y.,Ito, K.,Yoshimoto, T. (deposition date: 2007-06-09, release date: 2008-02-19, Last modification date: 2011-07-13)
Primary citation
Xu, Y.,Nakajima, Y.,Ito, K.,Zheng, H.,Oyama, H.,Heiser, U.,Hoffmann, T.,Gartner, U.T.,Demuth, H.U.,Yoshimoto, T.
Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
J.Mol.Biol., 375:708-719, 2008
PubMed: 18042490 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2007.09.077
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21320.2%1.8%6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution