2Z3Z
Prolyl tripeptidyl aminopeptidase mutant E636A complexd with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dipeptidyl aminopeptidase IV | polymer | 706 | 79546.7 | 1 | UniProt (Q7MUW6) Pfam (PF00930) Pfam (PF00326) | Porphyromonas gingivalis | prolyl tripeptidyl aminopeptidase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | [(2R)-1-(L-ALANYL-L-ISOLEUCYL)PYRROLIDIN-2-YL]BORONIC ACID | non-polymer | 299.2 | 1 | Chemie (AIO) | |||
| 4 | D (A) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A: 39 - 732 (UniProt: Q7MUW6)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | expression tag |
| Arg 28 | - | expression tag |
| Gly 29 | - | expression tag |
| Ser 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| Gly 37 | - | expression tag |
| Ser 38 | - | expression tag |
| Ala 636 | Glu 636 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79546.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 395.2 | |
| All* | Total formula weight | 79942.0 |
