2EEP

Prolyl Tripeptidyl Aminopeptidase Complexed with an Inhibitor

Summary for 2EEP

Entry DOI	10.2210/pdb2eep/pdb
Related	2D5L 2DCM
Descriptor	Dipeptidyl aminopeptidase IV, putative, SULFATE ION, [(2R)-1-(L-ALANYL-L-ISOLEUCYL)PYRROLIDIN-2-YL]BORONIC ACID, ... (4 entities in total)
Functional Keywords	peptidase family s9, prolyl oligopeptidase family, serine peptidase, inhibitor complex, hydrolase
Biological source	Porphyromonas gingivalis
Total number of polymer chains	1
Total formula weight	80000.02
Authors	Xu, Y.,Nakajima, Y.,Ito, K.,Yoshimoto, T. (deposition date: 2007-02-16, release date: 2008-02-19, Last modification date: 2023-10-25)
Primary citation	Xu, Y.,Nakajima, Y.,Ito, K.,Zheng, H.,Oyama, H.,Heiser, U.,Hoffmann, T.,Gartner, U.T.,Demuth, H.U.,Yoshimoto, T. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism J.Mol.Biol., 375:708-719, 2008 Cited by PubMed: 18042490 DOI: 10.1016/j.jmb.2007.09.077 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation