2YCX

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL

2YCX の概要

• エントリーDOI: 10.2210/pdb2ycx/pdb
• 関連するPDBエントリー: 1DEP 2VT4 2Y00 2Y01 2Y02 2Y03 2Y04 2YCW 2YCY 2YCZ
• 分子名称: BETA-1 ADRENERGIC RECEPTOR, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, octyl 1-thio-beta-D-glucopyranoside (3 entities in total)
• 機能のキーワード: receptor, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, thermostabilising point mutations, seven-helix receptor, 7tm receptor, gpcr
• 由来する生物種: MELEAGRIS GALLOPAVO (TURKEY)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73005.21

構造登録者

Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. (登録日: 2011-03-17, 公開日: 2011-06-01, 最終更新日: 2023-12-20)

• 主引用文献: Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.,Tate, C.G.,Schertler, G.F.; Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor.; Proc.Natl.Acad.Sci.USA, 108:8228-, 2011; PubMed: 21540331; DOI: 10.1073/PNAS.1100185108

実験手法

X-RAY DIFFRACTION (3.25 Å)