Caspase-8 in Complex with DARPin-8.4

Summary for 2Y1L

Related1QDU 1F9E 2C2Z 2FUN 1QTN 1I4E
DescriptorCASPASE-8, DARPIN-8.4, AC-IETD-CHO, ... (7 entities in total)
Functional Keywordshydrolase-inhibitor complex, devd darpin, ankyrin repeat protein, ribosome display, apoptosis, hydrolase/inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm Q14790 2Y1L
Total number of polymer chains8
Total molecular weight98112.76
Barandun, J.,Schroeder, T.,Mittl, P.R.E.,Grutter, M.G. (deposition date: 2010-12-08, release date: 2011-12-28, Last modification date: 2014-03-12)
Primary citation
Schroeder, T.,Barandun, J.,Grutter, M.G.
Caspase-8 in Complex with Darpin-8.4
To be Published,
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2182300.3%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2y1l
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Molmil generated image of 2y1l
rotated about x axis by 90°
Molmil generated image of 2y1l
rotated about y axis by 90°