1F9E
CASPASE-8 SPECIFICITY PROBED AT SUBSITE S4: CRYSTAL STRUCTURE OF THE CASPASE-8-Z-DEVD-CHO
Summary for 1F9E
Entry DOI | 10.2210/pdb1f9e/pdb |
Related | 1CP3 1PAU 1QDU 1QTN |
Related PRD ID | PRD_000331 |
Descriptor | CASPASE-8 ALPHA CHAIN, CASPASE-8 BETA CHAIN, (PHQ)DEVD, ... (4 entities in total) |
Functional Keywords | cysteine protease, caspase-8, flice, mch5, mach, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q14790 |
Total number of polymer chains | 18 |
Total formula weight | 169822.13 |
Authors | Blanchard, H.,Donepudi, M.,Tschopp, M.,Kodandapani, L.,Wu, J.C.,Grutter, M.G. (deposition date: 2000-07-10, release date: 2001-07-10, Last modification date: 2018-01-24) |
Primary citation | Blanchard, H.,Donepudi, M.,Tschopp, M.,Kodandapani, L.,Wu, J.C.,Grutter, M.G. Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex. J.Mol.Biol., 302:9-16, 2000 Cited by PubMed: 10964557DOI: 10.1006/jmbi.2000.4041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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