1F9E

CASPASE-8 SPECIFICITY PROBED AT SUBSITE S4: CRYSTAL STRUCTURE OF THE CASPASE-8-Z-DEVD-CHO

Summary for 1F9E

• Entry DOI: 10.2210/pdb1f9e/pdb
• Related: 1CP3 1PAU 1QDU 1QTN
• Related PRD ID: PRD_000331
• Descriptor: CASPASE-8 ALPHA CHAIN, CASPASE-8 BETA CHAIN, (PHQ)DEVD, ... (4 entities in total)
• Functional Keywords: cysteine protease, caspase-8, flice, mch5, mach, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q14790
• Total number of polymer chains: 18
• Total formula weight: 169822.13

Authors

Blanchard, H.,Donepudi, M.,Tschopp, M.,Kodandapani, L.,Wu, J.C.,Grutter, M.G. (deposition date: 2000-07-10, release date: 2001-07-10, Last modification date: 2018-01-24)

• Primary citation: Blanchard, H.,Donepudi, M.,Tschopp, M.,Kodandapani, L.,Wu, J.C.,Grutter, M.G.; Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex.; J.Mol.Biol., 302:9-16, 2000; PubMed: 10964557; DOI: 10.1006/jmbi.2000.4041

Experimental method

X-RAY DIFFRACTION (2.9 Å)