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2XYQ

Crystal structure of the nsp16 nsp10 SARS coronavirus complex

2XYQ の概要
エントリーDOI10.2210/pdb2xyq/pdb
関連するPDBエントリー1O5S 1P76 1P9T 1PA5 1PUK 1Q1X 1SXF 1UJ1 1UK2 1UK3 1UK4 1UW7 1WOF 1YSY 1Z1I 1Z1J 2A5A 2A5I 2A5K 2ACF 2AHM 2AMD 2AMQ 2BX3 2BX4 2C3S 2D2D 2V6N 2XYR 2XYV
分子名称PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, CHLORIDE ION, ... (8 entities in total)
機能のキーワードtransferase-viral protein complex, rossmann fold, transferase/viral protein
由来する生物種SARS CORONAVIRUS
詳細
細胞内の位置Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X7 P0C6X7
タンパク質・核酸の鎖数2
化学式量合計46400.89
構造登録者
Decroly, E.,Debarnot, C.,Ferron, F.,Bouvet, M.,Coutard, B.,Imbert, I.,Gluais, L.,Papageorgiou, N.,Ortiz-Lombardia, M.,Lescar, J.,Canard, B. (登録日: 2010-11-18, 公開日: 2011-10-19, 最終更新日: 2023-12-20)
主引用文献Decroly, E.,Debarnot, C.,Ferron, F.,Bouvet, M.,Coutard, B.,Imbert, I.,Gluais, L.,Papageorgiou, N.,Sharff, A.,Bricogne, G.,Ortiz-Lombardia, M.,Lescar, J.,Canard, B.
Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7:2059-, 2011
Cited by
PubMed: 21637813
DOI: 10.1371/JOURNAL.PPAT.1002059
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2 Å)
構造検証レポート
Validation report summary of 2xyq
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-09-18に公開中

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