2V6N
Crystal structures of the SARS-coronavirus main proteinase inactivated by benzotriazole compounds
Summary for 2V6N
Entry DOI | 10.2210/pdb2v6n/pdb |
Descriptor | REPLICASE POLYPROTEIN 1AB, 4-(DIMETHYLAMINO)BENZOIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | thiol protease, rna replication, main proteinase, ribosomal frameshift, sars, protease, hydrolase, polyprotein, viral protein |
Biological source | HUMAN SARS CORONAVIRUS (SARS-COV) |
Total number of polymer chains | 1 |
Total formula weight | 34333.13 |
Authors | Verschueren, K.H.G.,Pumpor, K.,Anemueller, S.,Mesters, J.R.,Hilgenfeld, R. (deposition date: 2007-07-19, release date: 2008-07-01, Last modification date: 2023-12-13) |
Primary citation | Verschueren, K.H.G.,Pumpor, K.,Anemueller, S.,Chen, S.,Mesters, J.R.,Hilgenfeld, R. A Structural View of the Inactivation of the Sars Coronavirus Main Proteinase by Benzotriazole Esters. Chem.Biol., 15:597-, 2008 Cited by PubMed: 18559270DOI: 10.1016/J.CHEMBIOL.2008.04.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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