2XRL
Tet-repressor class D T103A with doxycycline
Summary for 2XRL
Entry DOI | 10.2210/pdb2xrl/pdb |
Related | 1A6I 1BJ0 1BJY 1BJZ 1DU7 1ORK 1QPI 2TCT 2TRT 2VKE 2VKV 2X6O 2X9D 2XB5 2XGC 2XGD 2XGE 2XPS 2XPT 2XPU 2XPV 2XPW 3ZQF 3ZQG 3ZQH 3ZQI |
Descriptor | TETRACYCLINE REPRESSOR PROTEIN CLASS D, CHLORIDE ION, (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, ... (5 entities in total) |
Functional Keywords | transcription, antibiotic resistance, dna-binding, helix-turn-helix |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 1 |
Total formula weight | 23797.95 |
Authors | Palm, G.J.,Waack, P.,Hinrichs, W. (deposition date: 2010-09-16, release date: 2011-10-05, Last modification date: 2023-12-20) |
Primary citation | Palm, G.J.,Buchholz, I.,Werten, S.,Girbardt, B.,Berndt, L.,Delcea, M.,Hinrichs, W. Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868:140404-140404, 2020 Cited by PubMed: 32114262DOI: 10.1016/j.bbapap.2020.140404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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