2XAC

Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity

2XAC の概要

• エントリーDOI: 10.2210/pdb2xac/pdb
• 関連するPDBエントリー: 1FLT 1QSV 1QSZ 1QTY 1RV6 2C7W 2VWE
• 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR B, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: transferase-signaling protein complex, angiogenesis, cysteine-knot protein, mitogen, transferase, signaling protein, transferase/signaling protein
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Secreted: P49765; Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 44826.06

構造登録者

Iyer, S.,Darley, P.,Acharya, K.R. (登録日: 2010-03-30, 公開日: 2010-05-19, 最終更新日: 2023-12-20)

• 主引用文献: Iyer, S.,Darley, P.,Acharya, K.R.; Structural Insights Into the Binding of Vegf-B by Vegfr-1D2: Recognition and Specificity; J.Biol.Chem., 285:23779-, 2010; PubMed: 20501651; DOI: 10.1074/JBC.M110.130658

実験手法

X-RAY DIFFRACTION (2.71 Å)