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2WO7

Isopenicillin N synthase with substrate analogue L,L,D-ACd2Ab (unexposed)

Summary for 2WO7
Entry DOI10.2210/pdb2wo7/pdb
Related1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVI 2IVJ 2JB4 2VAU 2VBB 2VBD 2VBP 2VCM 2VE1
DescriptorISOPENICILLIN N SYNTHASE, FE (II) ION, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, ... (4 entities in total)
Functional Keywordsoxidoreductase, b-lactam antibiotic, metal-binding, monocyclic intermediate, oxygenase, penicillin biosynthesis
Biological sourceEMERICELLA NIDULANS
Total number of polymer chains1
Total formula weight37967.07
Authors
Ge, W.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (deposition date: 2009-07-22, release date: 2010-07-21, Last modification date: 2023-12-20)
Primary citationGe, W.,Clifton, I.J.,Stok, J.E.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.
Crystallographic Studies on the Binding of Selectively Deuterated Lld- and Lll-Substrate Epimers by Isopenicillin N Synthase.
Biochem.Biophys.Res.Commun., 398:659-, 2010
Cited by
PubMed: 20603104
DOI: 10.1016/J.BBRC.2010.06.129
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

数据于2024-03-27公开中

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