2WO7
Isopenicillin N synthase with substrate analogue L,L,D-ACd2Ab (unexposed)
Summary for 2WO7
Entry DOI | 10.2210/pdb2wo7/pdb |
Related | 1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVI 2IVJ 2JB4 2VAU 2VBB 2VBD 2VBP 2VCM 2VE1 |
Descriptor | ISOPENICILLIN N SYNTHASE, FE (II) ION, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, ... (4 entities in total) |
Functional Keywords | oxidoreductase, b-lactam antibiotic, metal-binding, monocyclic intermediate, oxygenase, penicillin biosynthesis |
Biological source | EMERICELLA NIDULANS |
Total number of polymer chains | 1 |
Total formula weight | 37967.07 |
Authors | Ge, W.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (deposition date: 2009-07-22, release date: 2010-07-21, Last modification date: 2023-12-20) |
Primary citation | Ge, W.,Clifton, I.J.,Stok, J.E.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. Crystallographic Studies on the Binding of Selectively Deuterated Lld- and Lll-Substrate Epimers by Isopenicillin N Synthase. Biochem.Biophys.Res.Commun., 398:659-, 2010 Cited by PubMed: 20603104DOI: 10.1016/J.BBRC.2010.06.129 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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