2VCM
Isopenicillin N synthase with substrate analogue AsMCOV
Summary for 2VCM
Entry DOI | 10.2210/pdb2vcm/pdb |
Related | 1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVI 2IVJ 2JB4 2VAU 2VBB 2VBD 2VBP |
Descriptor | ISOPENICILLIN N SYNTHETASE, FE (II) ION, N^6^-[(1R,2S)-1-({[(1R)-1-carboxy-2-methylpropyl]oxy}carbonyl)-2-sulfanylpropyl]-6-oxo-L-lysine, ... (5 entities in total) |
Functional Keywords | antibiotic biosynthesis, penicillin biosynthesis, iron, oxygenase, vitamin c, metal-binding, monocyclic intermediate, oxidoreductase, b-lactam antibiotic |
Biological source | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Total number of polymer chains | 1 |
Total formula weight | 38190.25 |
Authors | Ge, W.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (deposition date: 2007-09-25, release date: 2008-11-04, Last modification date: 2024-05-08) |
Primary citation | Ge, W.,Clifton, I.J.,Howard-Jones, A.R.,Stok, J.E.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue. Chembiochem, 10:2025-, 2009 Cited by PubMed: 19598184DOI: 10.1002/CBIC.200900080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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