2WKQ

Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant

2WKQ の概要

• エントリーDOI: 10.2210/pdb2wkq/pdb
• 関連するPDBエントリー: 1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2V0U 2V0W 2V1A 2V1B 2VRW 2WKP 2WKR
• 分子名称: NPH1-1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, GUANOSINE-5'-TRIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: transferase, cell adhesion, nucleotide-binding, protein engineering, ras superfamily lov2, phototropin1, protein design, small g-protein, light- induced signal transduction, lov2, gtpase, rho family, atp-binding, chimera, nucleotide-binding protein engineering, light-induced signal transduction, alternative splicing, cell membrane, adp-ribosylation, lipoprotein, gtp-binding
• 由来する生物種: AVENA SATIVA (OAT); 詳細
• 細胞内の位置: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38805.24

構造登録者

Wu, Y.I.,Frey, D.,Lungu, O.I.,Jaehrig, A.,Schlichting, I.,Kuhlman, B.,Hahn, K.M. (登録日: 2009-06-16, 公開日: 2009-08-18, 最終更新日: 2023-12-13)

• 主引用文献: Wu, Y.I.,Frey, D.,Lungu, O.I.,Jaehrig, A.,Schlichting, I.,Kuhlman, B.,Hahn, K.M.; A Genetically Encoded Photoactivatable Rac Controls the Motility of Living Cells.; Nature, 461:104-, 2009; PubMed: 19693014; DOI: 10.1038/NATURE08241

実験手法

X-RAY DIFFRACTION (1.6 Å)