2WBJ

TCR complex

2WBJ の概要

• エントリーDOI: 10.2210/pdb2wbj/pdb
• 関連するPDBエントリー: 1A6A 1AQD 1BX2 1D5M 1D5X 1D5Z 1D6E 1DLH 1FV1 1FYT 1H15 1HQR 1HXY 1J8H 1JWM 1JWS 1JWU 1KG0 1KLG 1KLU 1LO5 1SEB 1SJE 1SJH 1T5W 1T5X 1YMM 1ZGL 2G9H 2SEB
• 分子名称: HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-15 BETA CHAIN, OB TCR, ... (7 entities in total)
• 機能のキーワード: transmembrane, immune response, t cell receptor, mhc ii, membrane, receptor, molecular mimicry, multiple sclerosis, immune system, autoimmunity, glycoprotein, mhc class ii
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 203970.30

構造登録者

Harkiolaki, M.,Holmes, S.L.,Svendsen, P.,Gregersen, J.W.,Jensen, L.T.,McMahon, R.,Friese, M.A.,van Boxel, G.,Etzensperger, R.,Tzartos, J.S.,Kranc, K.,Sainsbury, S.,Harlos, K.,Mellins, E.D.,Palace, J.,Esiri, M.M.,van der Merwe, P.A.,Jones, E.Y.,Fugger, L. (登録日: 2009-03-02, 公開日: 2009-04-07, 最終更新日: 2023-12-13)

• 主引用文献: Harkiolaki, M.,Holmes, S.L.,Svendsen, P.,Gregersen, J.W.,Jensen, L.T.,Mcmahon, R.,Friese, M.A.,Van Boxel, G.,Etzensperger, R.,Tzartos, J.S.,Kranc, K.,Sainsbury, S.,Harlos, K.,Mellins, E.D.,Palace, J.,Esiri, M.M.,Van Der Merwe, P.A.,Jones, E.Y.,Fugger, L.; T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.; Immunity, 30:348-, 2009; PubMed: 19303388; DOI: 10.1016/J.IMMUNI.2009.01.009

実験手法

X-RAY DIFFRACTION (3 Å)