2W2V

Rac2 (G12V) in complex with GTPgS

Summary for 2W2V

Entry DOI	10.2210/pdb2w2v/pdb
Related	1DS6 2W2T 2W2W 2W2X
Descriptor	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	adp-ribosylation, cytoplasm, disease mutation, gtp-binding, lipoprotein, methylation, nucleotide-binding, polymorphism, prenylation, signaling protein, phospholipase c, phosphoinositides, rho
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	83057.66
Authors	Opaleye, O.,Bunney, T.D.,Roe, S.M.,Pearl, L.H. (deposition date: 2008-11-04, release date: 2009-05-05, Last modification date: 2024-05-01)
Primary citation	Bunney, T.D.,Opaleye, O.,Roe, S.M.,Vatter, P.,Baxendale, R.W.,Walliser, C.,Everett, K.L.,Josephs, M.B.,Christow, C.,Rodrigues-Lima, F.,Gierschik, P.,Pearl, L.H.,Katan, M. Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2. Mol.Cell, 34:223-, 2009 Cited by PubMed: 19394299 DOI: 10.1016/J.MOLCEL.2009.02.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation