2W2V

Rac2 (G12V) in complex with GTPgS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2	polymer	184	20241.2	4	UniProt (P15153) Pfam (PF00071)	HOMO SAPIENS (HUMAN)	RAC2, P21-RAC2, SMALL G PROTEIN, GX
2	E, F, G, H (A, B, C, D)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	4	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
3	I, J, K, L (A, B, C, D)	water	water		18.0	527	Chemie (HOH)

Sequence modifications

A, B, C, D: -6 - 0 (PDB: 2W2V)
A, B, C, D: 1 - 177 (UniProt: P15153)

PDB	External Database	Details
Val 12	Gly 12	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80964.9
Non-Polymers*	Number of molecules	4
	Total formula weight	2092.7
All*	Total formula weight	83057.7

*Water molecules are not included.