2W2V
Rac2 (G12V) in complex with GTPgS
Summary for 2W2V
Entry DOI | 10.2210/pdb2w2v/pdb |
Related | 1DS6 2W2T 2W2W 2W2X |
Descriptor | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | adp-ribosylation, cytoplasm, disease mutation, gtp-binding, lipoprotein, methylation, nucleotide-binding, polymorphism, prenylation, signaling protein, phospholipase c, phosphoinositides, rho |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 83057.66 |
Authors | Opaleye, O.,Bunney, T.D.,Roe, S.M.,Pearl, L.H. (deposition date: 2008-11-04, release date: 2009-05-05, Last modification date: 2024-05-01) |
Primary citation | Bunney, T.D.,Opaleye, O.,Roe, S.M.,Vatter, P.,Baxendale, R.W.,Walliser, C.,Everett, K.L.,Josephs, M.B.,Christow, C.,Rodrigues-Lima, F.,Gierschik, P.,Pearl, L.H.,Katan, M. Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2. Mol.Cell, 34:223-, 2009 Cited by PubMed: 19394299DOI: 10.1016/J.MOLCEL.2009.02.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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