2VT4

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL

2VT4 の概要

• エントリーDOI: 10.2210/pdb2vt4/pdb
• 関連するPDBエントリー: 1DEP 2R4R 2R4S 2RH1
• 分子名称: BETA1 ADRENERGIC RECEPTOR, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: gpcr, membrane, receptor, palmitate, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, g protein coupled receptor, thermostabilising point mutations, phosphoprotein, seven-helix receptor, lipoprotein, 7tm receptor, glycoprotein, transmembrane
• 由来する生物種: MELEAGRIS GALLOPAVO (COMMON TURKEY)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 148237.55

構造登録者

Warne, A.,Serrano-Vega, M.J.,Baker, J.G.,Moukhametzianov, R.,Edwards, P.C.,Henderson, R.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. (登録日: 2008-05-09, 公開日: 2008-06-24, 最終更新日: 2023-12-13)

• 主引用文献: Warne, A.,Serrano-Vega, M.J.,Baker, J.G.,Moukhametzianov, R.,Edwards, P.C.,Henderson, R.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X.; Structure of a Beta1-Adrenergic G-Protein-Coupled Receptor.; Nature, 454:486-, 2008; PubMed: 18594507; DOI: 10.1038/NATURE07101

実験手法

X-RAY DIFFRACTION (2.7 Å)