2VSL
Crystal Structure of XIAP BIR3 with a Bivalent Smac Mimetic
Summary for 2VSL
Entry DOI | 10.2210/pdb2vsl/pdb |
Related | 1C9Q 1F9X 1G3F 1G73 1I3O 1I4O 1I51 1KMC 1NW9 1TFQ 1TFT 2JK7 |
Descriptor | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, PEPTIDE (MAA-LYS-PRO-PHE), POLYETHYLENE GLYCOL (N=34), ... (5 entities in total) |
Functional Keywords | zinc-finger, polymorphism, smac mimetic, metal-binding, ubl conjugation pathway, thiol protease inhibitor, phosphoprotein, ubl conjugation, protease inhibitor, bir3, zinc, xiap, ligase, apoptosis, cytoplasm, hydrolase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm: P98170 |
Total number of polymer chains | 2 |
Total formula weight | 13161.22 |
Authors | Meagher, J.L.,Stuckey, J.A. (deposition date: 2008-04-24, release date: 2008-09-02, Last modification date: 2024-05-01) |
Primary citation | Nikolovska-Coleska, Z.,Meagher, J.L.,Jiang, S.,Yang, C.Y.,Qiu, S.,Roller, P.P.,Stuckey, J.A.,Wang, S. Interaction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein. Biochemistry, 47:9811-, 2008 Cited by PubMed: 18717598DOI: 10.1021/BI800785Y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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