2VR3

Structural and Biochemical Characterization of Fibrinogen binding to ClfA from Staphylocccus aureus

2VR3 の概要

• エントリーDOI: 10.2210/pdb2vr3/pdb
• 関連するPDBエントリー: 1DUG 1FIB 1FIC 1FID 1FZA 1FZB 1FZC 1FZE 1FZF 1FZG 1LT9 1LTJ 1N86 1N8E 1RE3 1RE4 1RF0 1RF1 2FFD 2FIB 3FIB
• 分子名称: CLUMPING FACTOR A, FIBRINOGEN GAMMA-CHAIN (3 entities in total)
• 機能のキーワード: platelet aggregation, peptidoglycan-anchor, cell adhesion, staphylococcus aureus, fibrinogen gamma-chain, secreted, cell wall, virulence, clumping factor
• 由来する生物種: STAPHYLOCOCCUS AUREUS; 詳細
• 細胞内の位置: Secreted, cell wall; Peptidoglycan-anchor (Potential): Q2G015; Secreted: P02679
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 74155.80

構造登録者

Ganesh, V.K.,Rivera, J.J.,Smeds, E.,Bowden, M.G.,Wann, E.R.,Gurusidappa, S.,Fitzgerald, J.R.,Hook, M. (登録日: 2008-03-25, 公開日: 2009-05-19, 最終更新日: 2023-12-13)

• 主引用文献: Ganesh, V.K.,Rivera, J.J.,Smeds, E.,Ko, Y.P.,Bowden, M.G.,Wann, E.R.,Gurusiddappa, S.,Fitzgerald, J.R.,Hook, M.; A Structural Model of the Staphylococcus Aureus Clfa-Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics.; Plos Pathog., 4:226-, 2008; PubMed: 19043557; DOI: 10.1371/JOURNAL.PPAT.1000226

実験手法

X-RAY DIFFRACTION (1.95 Å)