2VR3

Structural and Biochemical Characterization of Fibrinogen binding to ClfA from Staphylocccus aureus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CLUMPING FACTOR A	polymer	329	35801.5	2	UniProt (Q2G015) Pfam (PF17961) Pfam (PF10425) In PDB	STAPHYLOCOCCUS AUREUS	FIBRINOGEN-BINDING PROTEIN A, FIBRINOGEN RECEPTOR A
2	C, D	FIBRINOGEN GAMMA-CHAIN	polymer	13	1276.4	2	UniProt (P02679) In PDB	HOMO SAPIENS
3		water	water		18.0	527	Chemie (HOH)

Sequence modifications

A, B: 217 - 228 (PDB: 2VR3)
A, B: 229 - 545 (UniProt: Q2G015)

PDB	External Database	Details
Cys 327	Asp 327	engineered mutation
Cys 541	Lys 541	engineered mutation

C, D: 399 - 411 (UniProt: P02679)

PDB	External Database	Details
Ala 410	Asp 436	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	74155.8
All*	Total formula weight	74155.8

*Water molecules are not included.