2VFX
Structure of the Symmetric Mad2 Dimer
Summary for 2VFX
Entry DOI | 10.2210/pdb2vfx/pdb |
Related | 1DUJ 1GO4 1KLQ 1S2H 2V64 |
Descriptor | MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | mad2, mad1, cdc2, nucleus, mitosis, anaphase, cell cycle, cell division, spindle checkpoint, anaphase-promoting complex |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 12 |
Total formula weight | 288684.83 |
Authors | Yang, M.,Li, B.,Liu, C.-J.,Tomchick, D.R.,Machius, M.,Rizo, J.,Yu, H.,Luo, X. (deposition date: 2007-11-05, release date: 2008-03-18, Last modification date: 2023-12-13) |
Primary citation | Yang, M.,Li, B.,Liu, C.-J.,Tomchick, D.R.,Machius, M.,Rizo, J.,Yu, H.,Luo, X. Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol., 6:E50-, 2008 Cited by PubMed: 18318601DOI: 10.1371/JOURNAL.PBIO.0060050 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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