2VDP

Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV

2VDP の概要

• エントリーDOI: 10.2210/pdb2vdp/pdb
• 関連するPDBエントリー: 1DPK 1DPQ 1JV2 1JX5 1KUP 1KUZ 1L5G 1M1X 1M8O 1MIZ 1MK7 1MK9 1RN0 1S4W 1S4X 1TYE 1U8C 1UV9 2VC2 2VDK 2VDL 2VDM 2VDN 2VDO 2VDQ 2VDR
• 分子名称: INTEGRIN ALPHA-IIB, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (12 entities in total)
• 機能のキーワード: cell adhesion-immune system complex, fibrinogen binding, platelet integrin alphaiibbeta3, glycoprotein, cell adhesion, membrane, integrin, receptor, antagonist, host-virus interaction, pyrrolidone carboxylic acid, transmembrane, phosphorylation, disease mutation, cleavage on pair of basic residues, cell adhesion/immune system
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 151273.71

構造登録者

Springer, T.A.,Zhu, J.,Xiao, T. (登録日: 2007-10-10, 公開日: 2008-09-02, 最終更新日: 2020-07-29)

• 主引用文献: Springer, T.A.,Zhu, J.,Xiao, T.; Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.; J.Cell Biol., 182:791-, 2008; PubMed: 18710925; DOI: 10.1083/JCB.200801146

実験手法

X-RAY DIFFRACTION (2.8 Å)