2VD6
Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate.
Summary for 2VD6
Entry DOI | 10.2210/pdb2vd6/pdb |
Related | 2J91 |
Descriptor | ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, FUMARIC ACID, ... (7 entities in total) |
Functional Keywords | purine biosynthesis, lyase, epilepsy, purine metabolism |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 231327.86 |
Authors | Stenmark, P.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Tresaugues, L.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2007-09-30, release date: 2007-10-23, Last modification date: 2023-12-13) |
Primary citation | Stenmark, P.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P. Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate. To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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