2VBD
Isopenicillin N synthase with substrate analogue L,L,L-ACOMP (unexposed)
Summary for 2VBD
Entry DOI | 10.2210/pdb2vbd/pdb |
Related | 1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVI 2IVJ 2JB4 2VAU 2VBB |
Descriptor | ISOPENICILLIN N SYNTHETASE, FE (II) ION, N^6^-[(1R)-2-[(1R)-1-carboxy-2-(methylsulfanyl)ethoxy]-2-oxo-1-(sulfanylmethyl)ethyl]-6-oxo-L-lysine, ... (4 entities in total) |
Functional Keywords | antibiotic biosynthesis, penicillin biosynthesis, iron, oxygenase, vitamin c, metal-binding, monocyclic intermediate, oxidoreductase, b-lactam antibiotic |
Biological source | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Total number of polymer chains | 1 |
Total formula weight | 38002.13 |
Authors | Ge, W.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (deposition date: 2007-09-10, release date: 2008-09-23, Last modification date: 2024-05-08) |
Primary citation | Ge, W.,Clifton, I.J.,Stok, J.E.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. The Crystal Structure of an Lll-Configured Depsipeptide Substrate Analogue Bound to Isopenicillin N Synthase. Org.Biomol.Chem., 8:122-, 2010 Cited by PubMed: 20024142DOI: 10.1039/B910170E PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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