2QKI

Human C3c in complex with the inhibitor compstatin

2QKI の概要

• エントリーDOI: 10.2210/pdb2qki/pdb
• 関連するPDBエントリー: 1A1P 2A73 2A74 2I07 2ICE 2ICF
• 分子名称: Complement C3, compstatin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: immunity, complement inhibitor design, c3, compstatin, immune system-hydrolase inhibitor complex, immune system/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01024 P01024 P01024
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 273113.36

構造登録者

Janssen, B.J.C.,Halff, E.F.,Lambris, J.D.,Gros, P. (登録日: 2007-07-11, 公開日: 2007-08-14, 最終更新日: 2023-08-30)

• 主引用文献: Janssen, B.J.,Halff, E.F.,Lambris, J.D.,Gros, P.; Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.; J.Biol.Chem., 282:29241-29247, 2007; PubMed: 17684013; DOI: 10.1074/jbc.M704587200

実験手法

X-RAY DIFFRACTION (2.4 Å)