2OL4
Crystal structure of plasmodium falciparum enoyl ACP reductase with triclosan reductase
Summary for 2OL4
Entry DOI | 10.2210/pdb2ol4/pdb |
Related | 1NHD 1NHG 1NHW 1NNU 1ZSN 1ZW1 |
Descriptor | Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(2,4-DICHLOROPHENOXY)-5-(3-PHENYLPROPYL)PHENOL, ... (4 entities in total) |
Functional Keywords | pfenr, malaria, triclosan analog, oxidoreductase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Total number of polymer chains | 2 |
Total formula weight | 78772.01 |
Authors | Tsai, H. (deposition date: 2007-01-18, release date: 2007-07-17, Last modification date: 2023-08-30) |
Primary citation | Freundlich, J.S.,Wang, F.,Tsai, H.-C.,Kuo, M.,Shieh, H.-M.,Anderson, J.W.,Nkrumah, L.J.,Valderramos, J.-C.,Yu, M.,Kumar, T.R.S.,Valderramos, S.G.,Jacobs, W.R.,Schiehser, G.A.,Jacobus, D.P.,Fidock, D.A.,Sacchettini, J.C. X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy J.Biol.Chem., 282:25436-25444, 2007 Cited by PubMed: 17567585DOI: 10.1074/jbc.M701813200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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