1NHG
CRYSTAL STRUCTURE ANALYSIS OF PLASMODIUM FALCIPARUM ENOYL-ACYL-CARRIER-PROTEIN REDUCTASE WITH TRICLOSAN
Summary for 1NHG
Entry DOI | 10.2210/pdb1nhg/pdb |
Related | 1NHD 1NHW |
Descriptor | enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total) |
Functional Keywords | rossmann fold, short chain dehydrogenase reductase, nadh, oxidoreductase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) More |
Total number of polymer chains | 4 |
Total formula weight | 67054.43 |
Authors | Perozzo, R.,Kuo, M.,Sidhu, A.S.,Valiyaveettil, J.T.,Bittman, R.,Jacobs Jr., W.R.,Fidock, D.A.,Sacchettini, J.C. (deposition date: 2002-12-19, release date: 2003-02-25, Last modification date: 2024-02-14) |
Primary citation | Perozzo, R.,Kuo, M.,Sidhu, A.S.,Valiyaveettil, J.T.,Bittman, R.,Jacobs Jr., W.R.,Fidock, D.A.,Sacchettini, J.C. Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase J.Biol.Chem., 277:13106-13114, 2002 Cited by PubMed: 11792710DOI: 10.1074/jbc.M112000200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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