2NZ6
Crystal structure of the PTPRJ inactivating mutant C1239S
Summary for 2NZ6
Entry DOI | 10.2210/pdb2nz6/pdb |
Related | 2CFV |
Descriptor | Receptor-type tyrosine-protein phosphatase eta, NICKEL (II) ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase receptor type tyrosine phosphatase j, ptprj, glycoprotein, protein phosphatase, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: Q12913 |
Total number of polymer chains | 1 |
Total formula weight | 37290.44 |
Authors | Ugochukwu, E.,Barr, A.,Savitsky, P.,Pike, A.C.W.,Bunkoczi, G.,Sundstrom, M.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-22, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136:352-363, 2009 Cited by PubMed: 19167335DOI: 10.1016/j.cell.2008.11.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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