2NZ6

Crystal structure of the PTPRJ inactivating mutant C1239S

Summary for 2NZ6

Entry DOI	10.2210/pdb2nz6/pdb
Related	2CFV
Descriptor	Receptor-type tyrosine-protein phosphatase eta, NICKEL (II) ION, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	hydrolase receptor type tyrosine phosphatase j, ptprj, glycoprotein, protein phosphatase, structural genomics, structural genomics consortium, sgc, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type I membrane protein: Q12913
Total number of polymer chains	1
Total formula weight	37290.44
Authors	Ugochukwu, E.,Barr, A.,Savitsky, P.,Pike, A.C.W.,Bunkoczi, G.,Sundstrom, M.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-22, release date: 2006-12-12, Last modification date: 2023-08-30)
Primary citation	Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136:352-363, 2009 Cited by PubMed: 19167335 DOI: 10.1016/j.cell.2008.11.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation