Crystal structure of the PTPRJ inactivating mutant C1239S

Summary for 2NZ6

DescriptorReceptor-type tyrosine-protein phosphatase eta, NICKEL (II) ION, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordshydrolase receptor type tyrosine phosphatase j, ptprj, glycoprotein, protein phosphatase, structural genomics, structural genomics consortium, sgc, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein Q12913
Total number of polymer chains1
Total molecular weight37290.44
Primary citation
Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.
Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136:352-363, 2009
PubMed: 19167335 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2008.11.038
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22640.3%3.6%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report