2NT1
Structure of acid-beta-glucosidase at neutral pH
Summary for 2NT1
| Entry DOI | 10.2210/pdb2nt1/pdb |
| Related | 2NSX 2NT0 |
| Descriptor | Glucosylceramidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | acid-beta-glucosidase, cerezyme, glucosylceramide, gaucher disease, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 230853.24 |
| Authors | Lieberman, R.L.,Petsko, G.A.,Ringe, D. (deposition date: 2006-11-06, release date: 2006-12-26, Last modification date: 2023-08-30) |
| Primary citation | Lieberman, R.L.,Wustman, B.A.,Huertas, P.,Powe, A.C.,Pine, C.W.,Khanna, R.,Schlossmacher, M.G.,Ringe, D.,Petsko, G.A. Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease. Nat.Chem.Biol., 3:101-107, 2007 Cited by PubMed: 17187079DOI: 10.1038/nchembio850 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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