2NT1
Structure of acid-beta-glucosidase at neutral pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glucosylceramidase | polymer | 497 | 55640.2 | 4 | UniProt (P04062) Pfam (PF02055) Pfam (PF17189) | Homo sapiens (human) | Beta-glucocerebrosidase, Acid beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Alglucerase, Imiglucerase |
| 2 | AA, E, RB, TA (B, A, D, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 3 | AB, AC, BA, BB, BC... (C, D, B, A) | PHOSPHATE ION | non-polymer | 95.0 | 78 | Chemie (PO4) | |||
| 4 | IC, JC, KC, LC (A, B, C, D) | water | water | 18.0 | 1344 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 497 (UniProt: P04062)
| PDB | External Database | Details |
|---|---|---|
| His 495 | Arg 534 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222560.7 | |
| Non-Polymers* | Number of molecules | 82 |
| Total formula weight | 8292.6 | |
| All* | Total formula weight | 230853.2 |
