2NQD

Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin L

Summary for 2NQD

Entry DOI	10.2210/pdb2nqd/pdb
Related	1CS8 1ICF 2H7W 2NNR
Descriptor	Chagasin, Cathepsin L, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	chagasin-cathepsin l complex, three prong inhibition mode, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
Biological source	Trypanosoma cruzi More
Total number of polymer chains	2
Total formula weight	36694.87
Authors	Redzynia, I.,Bujacz, G.,Ljunggren, A.,Jaskolski, M.,Abrahamson, M. (deposition date: 2006-10-31, release date: 2007-07-24, Last modification date: 2023-10-25)
Primary citation	Ljunggren, A.,Redzynia, I.,Alvarez-Fernandez, M.,Abrahamson, M.,Mort, J.S.,Krupa, J.C.,Jaskolski, M.,Bujacz, G. Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371:137-153, 2007 Cited by PubMed: 17561110 DOI: 10.1016/j.jmb.2007.05.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation